Revolutionize the way we prevent, detect, and respond to major 21st century health security threats.


Our individual DRIVe programs accelerate the development and availability of transformative technologies and approaches to protect Americans from health security threats. We push the boundaries of innovation to tackle the biggest health security challenges.


Provide health information to individuals at early stages of infection, injury, or illness.

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Enhance the usability of 3D human tissue models (“tissue chips”) as tools for drug development.

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COVID-19 Response

Use pathogen-agnostic technologies from the ENACT and Solving Sepsis portfolios in response to COVID-19.

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Beyond The Needle

Develop alternative delivery methods for vaccines and other therapeutics.


Repurpose commonly available therapeutics to treat symptoms associated with chemical agent exposure.

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Solving Sepsis

Seek interventions to identify sepsis early resulting in improved patient outcomes and decreased mortality.

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Find out more about DRIVe upcoming events

COVID-19 Pivot of ENACT and Sepsis

Since March, we’ve invested in approaches to pilot and clinically validate technologies in advanced development, or that are FDA cleared, to be used by patients or healthcare providers in monitoring patients along the COVID-19 care continuum (pre-infection, symptomatic, infection, and recovery).

DRIVe's Impact

  • We change how government approaches big health security challenges and threats
  • We tackle health security threats by seeking breakthrough devices and technologies
  • We model our work on the best practices of the entrepreneurial world.
  • We use tools and authorities to support new technologies, streamline contracting processes, and launch a network of accelerators
  • The team is comprised of scientists and venture entrepreneurs dedicated to identifying threats to health security

Investing Process